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Product Datasheet

Catalog Number

ALP14431

Product Name

Recombinant Human Cxcl8/Chemokine Ligand 8 Protein

Product Description

ALP14431 Recombinant Human Cxcl8/Chemokine Ligand 8 Protein is expressed in Yeast.

Official Symbol

CXCL8

Protein Family

Intercrine Family

Expression Host

Yeast

Species

Human

Size

50ug

Molecular Weight

11 kDa

Endotoxin

< 1.0 EU/ug determined by the LAL method.

Purity

>= 97% as determined by SDS-PAGE

Formulation

Supplied as liquid or lyophilized powder

Bioactivity

Measured by its ability to induce myeloperoxidase release from cytochalasin Btreated human neutrophils. The ED50 for this effect is typically 0.15-0.35ug/mL. Measured by its ability to chemoattract human CXCR2 transfected BaF3 mouse proB cells.The ED50 for this effect is typically 0.5-2.5ng/mL.

Reconstitution

It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 100ug/ml.

Backgound

IL-8 was originally discovered as a neutrophil chemotactic and activating factor. It was also referred to as neutrophil chemotactic factor (NCF), neutrophil activating protein (NAP), monocytederived neutrophil chemotactic factor (MDNCF), Tlymphocyte chemotactic factor (TCF), granulocyte chemotactic protein (GCP) and leukocyte adhesion inhibitor (LAI).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.

Gene Name

CXCL8 chemokine (C-X-C motif) ligand 8 [ Homo sapiens ]

Gene ID

3576

 

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