Product Datasheet
|
Catalog Number |
ALP14306 |
|
Product Name |
Recombinant Human Cx3Cl1/Chemokine Ligand 1 Protein |
|
Product Description |
ALP14306 Recombinant Human Cx3Cl1/Chemokine Ligand 1 Protein is expressed in NSO Cells. |
|
Official Symbol |
CX3CL1 |
|
Protein Family |
Intercrine Family |
|
Expression Host |
NSO Cells |
|
Species |
Human |
|
Size |
50ug |
|
Molecular Weight |
90 kDa |
|
Endotoxin |
< 1.0 EU/ug determined by the LAL method. |
|
Purity |
>= 97% as determined by SDS-PAGE |
|
Backgound |
Fractalkine (FKN) is a transmembrane mucin-chemokine hybrid molecule expressed on activated endothelium that mediates attachment and firm adhesion of T cells, monocytes and NK cells. FKN plays an important proinflammatory role in rheumatoid arthritis (RA) pathogenesis as characterized by induction of synovial angiogenesis, chemotaxis, activation of monocytes and T cells as well as the stimulation of proliferation and synthesis of matrix degrading enzymes in synovial fibroblasts. |
|
Storage |
Store at -80°C. Avoid repeated freeze-thaw cycles. |
|
Shipping Condition |
In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
|
Gene Name |
CX3CL1 chemokine (C-X3-C motif) ligand 1 [ Homo sapiens ] |
|
Gene ID |
6376 |
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