Polyclonal antibodies are a group of antibodies that are produced by different B cells in response to a specific antigen. Unlike monoclonal antibodies, which are produced by a single clone of B cells, polyclonal antibodies recognize multiple epitopes on an antigen and can bind to different regions of the same protein. They are an essential tool in research, diagnostics, and therapeutics.
Polyclonal antibodies are produced by immunizing an animal (usually a rabbit or goat) with a specific antigen. The animal's immune system will recognize the foreign antigen and generate an immune response. The antibodies are then harvested from the animal's blood serum and purified. Polyclonal antibodies are widely used in research to detect and quantify the expression of a specific protein. They can be used in various techniques such as Western blotting, ELISA, immunoprecipitation, and immunocytochemistry. Polyclonal antibodies can also be used to neutralize the biological activity of a protein or to study the protein-protein interactions.
Advantages of Polyclonal Antibodies:
(1) Higher sensitivity: Polyclonal antibodies can recognize multiple epitopes on an antigen, which increases the sensitivity of the assay.
(2) Lower cost: Polyclonal antibodies are less expensive to produce than monoclonal antibodies.
(3) Easier production: Polyclonal antibodies can be produced in large quantities by immunization and serum purification only.
(4) Diversity: Polyclonal antibodies can recognize different regions of the same protein, which increases the chances of detecting a specific protein in different assays.
Alpha Lifetech Inc. can offer over 10,000 polyclonal antibodies from different species to satisfy the requirements of our customers. With our well established platforms, we guarantee that the polyclonal antibodies we provide are validated through multiple applications and samples, strictly quality controlled and approved for research use. Further, if you wanna do a custom service, our technical support will provide with a specific proposal and quote.
With extensive experience in protein expression, antibody development, library construction, cell line construction, and other related services, we are dedicated to accelerate your research. Please check our list to choose the polyclonal antibodies you want. For more information, please contact us and our technical support team will get back to you as soon as possible.
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