Alpha Lifetech Inc. devotes all efforts to CRO services for years. Alpha Lifetech Inc. has provided peptide synthesis and peptide labeling, modification (phosphorylation, methylation, biotinylation, glycosylation, cyclization, or attachment to carrier proteins or dye labels) service to worldwide customers every year. According to our strict quality-assured system, we promise to provide peptides with high purity at a lower price. All peptides will be verified under HPLC and LC-MS.
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Custom Peptide Synthesis Service – Peptide Design & Synthesis Services
Peptides can be synthesized in vitro and used as antigens to produce antibodies in animals or used as ligands for immune-affinity purification. Sometimes, it is hard to express and collect some special biomolecules in vivo by conventional methods, such as the production of phospho-specific antibodies; whereas it will be much easier to produce phospho-specific antibodies by immunizing animals with phosphate-labeled peptides.
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As an experienced provider of high-quality peptide synthesis services, Alpha Lifetech Inc. selects the building blocks and resins carefully, deploys case-specific methods to circumvent hydrophobic interactions, and devises backup routes in the event of synthetic difficulties. |
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In addition, we provide a series of downstream services after peptides synthesis, shown in table 1.
Custom Peptide Synthesis - Specification-Table 1
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Categories |
Services |
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Peptide Form |
Single peptides |
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Peptide Scale |
mg to g scale |
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Peptide Purification |
HPLC purification up to 98% (Crude peptide also available) |
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Peptide Length |
Routine synthesis of peptides ≤ 30 aa. Long peptide synthesis using special chemistry (40-100 aa) |
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Modifications |
Phosphorylation-Tyr/Ser/Thr, Methylation, Acetylation, Biotinylation, Myristoylation and MAPS (4 or 8 chains) |
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Labels |
Isotope labels, PITC, FAM, FITC, Quantum and Rhodamine |
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Conjugations |
KLH, BSA, OVA, Hydralink |
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Cyclization |
S-S, N-C terminal, Lys, Asp, Glu |
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Analysis |
Liquid chromatography, mass spectrometry (LC/MS) |
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Peptide Libraries |
Customized |
Note: For more information about peptide modification and labeling, please find them in Peptide Structure Modification and Fluorescence & Stable Isotope Labeling
Example: A FAM-labeled synthesized peptide in breast cancer cells
| Confocal Image: the distribution of a short peptide labeled by the fluorescence group FAM in MDA-231 breast cancer cells. |
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Quantity Recommended For Different Applications
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Applications |
Quantity Recommended |
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Immuno-affinity purification |
≥15 mg resin-conjugated |
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Immunogen |
Large animal |
10-12 mg conjugated |
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Small animal |
4-6 mg conjugated |
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