Antibodies play an integral role in the immune defense against various pathogens. Due to the specificity and high affinity for their antigens, antibodies have been a valuable and indispensable tool in research. Today, various antibody products are marketed for research. They are potent tools for biochemical and biomedical research.
Antibody molecules are secreted as globular proteins. The antibody fragment (Fab) has the antigen binding site called the paratope, the lower part of the antibody consists of the crystallizable fragment (Fc), which binds to specific receptors to communicate with other components of the immune system. An antibody that can bind to a specific protein or a biomolecule of interest is called a primary antibody. Primary antibodies are produced as monoclonal or polyclonal antibodies usually using animal species such as the mouse, rabbit, rat and goat as hosts.
Monoclonal antibodies specifically detect a particular epitope on the antigen and therefore are less likely than polyclonal antibodies to cross-react with other proteins. The generation of monoclonal antibodies is initiated by an appropriate immune response induced by immunization of the animal. Today several animal species are used for monoclonal antibody generation such as rabbit, rat or sheep but the most common organism is still the mouse. Mouse mAbs are produced by hybrid cells formed by the fusion of mouse B cells and mouse myeloma cells.
Alpha Lifetech Inc. is a premier supplier of antibodies, proteins, ELISA kits, primary cells, cancer cell lines and related biological reagents, with extensive experience in protein expression, antibody development, library construction, cell line construction, and other related services. Alpha Lifetech Inc. offers thousands of mouse monoclonal antibodies targeted various biomolecules. Our product list covers Mouse Caspase-9 mAb, Mouse AKT1 mAb, Mouse VEGF mAb, Mouse VHL mAb, Mouse N6-methyladenosine/m6A mAb, Mouse HDAC1 mAb, etc.
With Alpha Lifetech Inc.'s well established platforms, we guarantee that the mouse monoclonal antibodies we provide are validated through multiple applications and samples, strictly quality controlled and approved for research use. Further, if you wanna do a custom service, our technical support will provide with a specific proposal and quote. Please check our list to choose the mouse monoclonal antibody you want. For more information, please contact us and our technical support team will get back to you as soon as possible.
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