Product Datasheet
Catalog Number |
ALP18746 |
Product Name |
Recombinant Human Fgf2/Fibroblast Growth Factor 2 Protein |
Product Description |
ALP18746 Recombinant Human Fgf2/Fibroblast Growth Factor 2 Protein is expressed in Escherichia coli. |
Official Symbol |
FGF2 |
Protein Family |
|
Expression Host |
Escherichia coli |
Species |
Human |
Size |
20ug |
Molecular Weight |
17.4 kDa |
Concentration |
0.172 mg/mL |
Endotoxin |
<1.0 EU/ug determined by the LAL method. |
Purity |
>= 97% as determined by SDS-PAGE |
Formulation |
Supplied as liquid or lyophilized powder |
Bioactivity |
The biological activity of recombinant human FGF basic was monitored in a mitogenic assay by measuring the FGF basic dependent 3H-thymidine incorporation in quiescent NR6R-3T3 fibroblasts (Rizzino, A. et al., 1988. Cancer Research 48:4266 - 4271). The ED50 for this effect is typically 0.1 - 0.25 ng/mL. |
Backgound |
FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35 - 60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. |
Shipping Condition |
In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
Gene Name |
FGF2 fibroblast growth factor 2 (basic) [ Homo sapiens ] |
Gene ID |
2247 |