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Product Datasheet

Catalog Number

ALP18746

Product Name

Recombinant Human Fgf2/Fibroblast Growth Factor 2 Protein

Product Description

ALP18746 Recombinant Human Fgf2/Fibroblast Growth Factor 2 Protein is expressed in Escherichia coli.

Official Symbol

FGF2

Protein Family

Heparin-Binding Growth Factor Family

Expression Host

Escherichia coli

Species

Human

Size

20ug

Molecular Weight

17.4 kDa

Concentration

0.172 mg/mL

Endotoxin

<1.0 EU/ug determined by the LAL method.

Purity

>= 97% as determined by SDS-PAGE

Formulation

Supplied as liquid or lyophilized powder

Bioactivity

The biological activity of recombinant human FGF basic was monitored in a mitogenic assay by measuring the FGF basic dependent 3H-thymidine incorporation in quiescent NR6R-3T3 fibroblasts (Rizzino, A. et al., 1988. Cancer Research 48:4266 - 4271). The ED50 for this effect is typically 0.1 - 0.25 ng/mL.

Backgound

FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35 - 60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway.

Shipping Condition

In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.

Gene Name

FGF2 fibroblast growth factor 2 (basic) [ Homo sapiens ]

Gene ID

2247

 

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