Product Datasheet
|
Catalog Number |
ALP1134 |
|
Product Name |
Human ACE2 Protein, His Tag, Avi Tag |
|
Description |
The Human ACE2 Protein(ALP1134) is produced in HEK293 Cells. |
|
Official Symbol |
ACE2 |
|
Expression Host |
HEK293 Cells |
|
Alias |
ACE-2, ACEH, ACE2 |
|
Species |
Human |
|
Size |
20ug, 100ug, 200ug |
|
Molecular Weight |
72.3 kDa |
|
Purification |
Affinity purification |
|
Endotoxin |
<1.0 EU/ug determined by the LAL method |
|
Purity |
>95% as determined by SDS-PAGE |
|
Buffer |
PBS, pH7.4 |
|
Background |
Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl. |
|
Storage |
Store at -80°C for long term storage. Avoid repeated freeze-thaw cycles. |
|
Shipping Condition |
In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
|
Gene ID |
59272 |
|
Note |
This product is for research use only. |
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