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Product Datasheet

Catalog Number

ALP30124

Product Name

Recombinant Zebrafish Lats1/Large Tumor Suppressor Kinase 1 Protein

Product Description

ALP30124 Recombinant Zebrafish Lats1/Large Tumor Suppressor Kinase 1 Protein is expressed in Mammalian Cells.

Official Symbol

LATS1

Protein Family

Protein Kinase (PK) Family

Expression Host

Mammalian Cells

Species

Zebrafish

Size

20ug

Endotoxin

< 1.0 EU/ug determined by the LAL method.

Purity

>= 80% as determined by SDS-PAGE

Buffer

PBS

Formulation

Supplied as liquid or lyophilized powder

Backgound

LATS1 is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis which is phosphorylated in a cell-cycle dependent manner. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity which indicating a role as a negative regulator of CDC2/cyclin A and the C-terminal kinase domain binds to its own N-terminal region.

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.

Gene Name

lats1 large tumor suppressor kinase 1 [ Danio rerio (zebrafish) ]

Gene ID

553164

 

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