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Product Datasheet

Catalog Number

ALP5001

Product Name

Recombinant Human 4-1Bb-L/Tumor Necrosis Factor Superfamily, Member 9 Protein

Product Description

ALP5001 Recombinant Human 4-1Bb-L/Tumor Necrosis Factor Superfamily, Member 9 Protein is expressed in Escherichia coli.

Official Symbol

4-1BB-L

Protein Family

Tumor Necrosis Family

Expression Host

Escherichia coli

Species

Human

Size

50ug

Molecular Weight

19.4 kDa

Endotoxin

< 1.0 EU/ug determined by the LAL method.

Purity

>= 95% as determined by SDS-PAGE

Formulation

Supplied as liquid or lyophilized powder

Bioactivity

Fully biologically active when compared to standard. The ED 50 determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml, corresponding to a specific activity of >1.0 × 10^5 IU/mg.

Reconstitution

We recommend that this vial be briefy centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. stock solutions should be apportion

Backgound

4-1BBL is a member of the tumor necrosis factor (TNF) receptor family. This receptor contributes to the clonal expansion, survival, and development of T cells.In addition, 4-1BBL expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has been shown to interact with TRAF2.

Storage

Store at -80°C for long term storage. Avoid repeated freeze-thaw cycles.

Shipping Condition

In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.

Gene Name

TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 [ Homo sapiens (human) ]

Gene ID

8744

 

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