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With years of providing antibody discovery services, Alpha Lifetech Inc. offers a unique approach to library creation. Alpha Lifetech Inc. can offer native, semi-synthesized and ful...
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The experts of Alpha Lifetech Inc. have extensive research experience in the R&D of pharmaceutical compounds. We can provide feasible advice and customized services for your project...
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Alpha Lifetech Inc. focuses on recombinant proteins' expression including prokaryotic, eukaryotic organism and novel high-potency recombinant proteins.
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Alpha Lifetech Inc. has developed and commercialized an integrated service covering native or synthesized library construction and screening, generation of specific monoclonal antib...
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As one of the premier protein suppliers, Alpha Lifetech Inc. can provide a variety of recombinant protein & antibody expression platforms along with a host of other protein services...
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Alpha Lifetech Inc. is experienced in cell line construction. We are committed to providing high-quality stable cell line construction services to customers worldwide. Our services ...
As a fast-growing global biological solution specialist, Alpha Lifetech Inc. has earned a reputation as a premium supplier known for exceptional quality, consistency and innovation.
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2023/12/03
Alpha Lifetech uses Thermo Fisher's Q ExactiveHF mass spectrometry platform, Orbitrap Fusion mass spectrometry platform, and Orbitrap Fusion Lumos mass spectrometry platform combined with Nano-LC, to provide SILAC-based CoIP-MS protein interaction analysis service packages.
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2023/11/07
Chimeric antibodies are antibodies that combine parental antibody variable regions and any acceptor constant area. Chimeric antibodies are hybrid molecules composed of different species’ domains.
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2023/10/30
Phage display is a laboratory technique for the study of protein–protein, protein–peptide, and protein–DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the genetic information that encodes them.
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2023/10/30
Enzymes are the workhorses of biological systems, orchestrating a vast array of chemical reactions necessary for life. Understanding their activity and the factors influencing it is essential in various scientific disciplines, from biochemistry to drug development. Enzyme kinetics is a powerful and widely used tool for characterizing enzyme behavior, providing critical insights into reaction rates, substrate affinity, and enzyme efficiency.
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2023/10/30
Mass spectrometry (MS) has emerged as a cornerstone technique in the field of proteomics, allowing scientists to identify and quantify proteins with unparalleled precision. In this technical support article, we will explore the fundamental principles of mass spectrometry for protein analysis, providing insights into its application and interpretation.
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2023/10/30
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful and versatile technique in the field of structural biology. Its applications in protein characterization are vast and impactful, enabling researchers to unravel the intricate details of protein structures and dynamics. In this technical support article, we will delve into the principles of NMR spectroscopy for protein analysis, guiding you through the essentials of its application and interpretation.
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2023/10/29
Understanding protein-protein interactions is pivotal in unraveling complex biological processes. A comprehensive understanding of these interactions sheds light on various cellular functions and enables the development of targeted therapeutics. In this technical support article, we will explore methods and insights into protein-protein interaction assays, highlighting key techniques employed in this field.
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2023/10/29
In the realm of molecular biology and protein biochemistry, scientists employ a variety of techniques to delve into the intricate world of proteins. One such fundamental method is SDS-PAGE, which stands for Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis. The core purpose of SDS-PAGE is to separate proteins based solely on their size. To grasp how this technique works, it's essential to dissect the two components of its name: SDS and PAGE.
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2023/10/29
Scientists have turned to the unique mechanisms of biology to craft these important proteins. We can synthesise proteins precisely by manipulating the genetic information encoded in the form of DNA, known as recombinant proteins.
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2023/10/27
Alpha Lifetech Inc., a pioneer in the realm of biotechnology, is making significant strides in the field of recombinant protein expression across diverse biosystems.
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2023/10/20
Antibodies are the sentinels of our immune system, fighting off foreign invaders with precision and efficiency. Over the years, these remarkable molecules have become invaluable tools in diagnostics and therapies. However, when it comes to using antibodies from other species in human medicine, challenges arise due to potential immune responses.
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2023/10/13
This year’s conference will bridge the gap between basic and applied science in micronutrient research. Organizers have brought together established research leaders, new investigators, and trainees to discuss a broad spectrum of topics in this unique area of study. Because of the interdisciplinary nature of biometals research, this conference is for all researchers involved in human health, nutrition, microbial pathogenesis, and structural biology.
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2023/09/28
Nuclear Bodies: Hubs of Genomic Activity focusing on molecular biology, cell biology, and biophysics of bodies situated within the cell nucleus.
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2023/09/25
Biology of Cilia and Flagella providing the premier forum to share the newest research. The program will cover the field from basic research in model organisms to the development of treatments for human ciliopathies.
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2023/09/18
Alterations in RNA processing have recently emerged as a new cancer hallmark and a promising target for cancer therapies. This inaugural Science Research Conference (SRC) explores how RNA processing contributes to cancer and how this process can be targeted for the development of novel cancer therapeutics.
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2023/09/16
The adaptive response is very focused and efficient in getting rid of invasive pathogens. However, it is essential for the immune system to discriminate between self and foreign chemicals in order to prevent harming the body's own components.
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2023/09/15
The Molecular Mechanisms of Immune Cell Development and Function Conference explores the fundamental mechanisms that control gene expression, differentiation, genome architecture, and function in diverse cell types in the immune system.
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2023/09/07
This inaugural FASEB Science Research Conference (SRC) offers a broad view of the factors associated with HIV pathogenesis or control of HIV infection in the absence of antiretroviral therapy (ART).
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2023/09/04
Alpha Lifetech is a reputable custom antibody services provider. Our Ph.D.-level specialists are very knowledgeable and skilled in phage display library construction. Our scientists are confident in their ability to provide one-stop service from target preparation to experiment design to meet your specific requirements.
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2023/08/31
Alpha Lifetech Inc. is a reputable custom antibody services provider. Our Ph.D.-level specialists are very knowledgeable and skilled in generating antibodies against small molecules. Our scientists are confident in their ability to provide one-stop service from target preparation, experiment design to antibody affinity maturation to meet your specific requirements.
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2023/08/25
Alpha Lifetech Inc. is a reputable custom antibody services provider. Our Ph.D.-level specialists are very knowledgeable and skilled in generating antibodies against small molecules. Our scientists are confident in their ability to provide one-stop service from target production, experiment design to antibody affinity maturation to meet your specific requirements.
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2023/08/23
Alpha Lifetech Inc. is a reputable custom antibody services provider. Our Ph.D.-level specialists are very knowledgeable and skilled in phage display library construction. Our scientists are confident in their ability to provide one-stop service from target preparation, experiment design to antibody affinity maturation to meet your specific requirements.
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2023/08/18
Protein kinases play a major role in cellular activation processes, including signal transduction by diverse immunoreceptors. Given their roles in cell growth and death and in the production of inflammatory mediators, targeting kinases has proven to be an effective treatment strategy, initially as anticancer therapies, but shortly thereafter in immune-mediated diseases.
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2023/08/14
This inaugural Science Research Conference (SRC), developed to complement the long-standing FASEB Gastrointestinal SRC, focuses on the gastrointestinal epithelial lining from the esophagus to the colon.
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2023/08/11
This Imaging Cellular and Chromosome Dynamics Conference is focused on the latest imaging techniques and delves into new assays and recent discoveries in the field.
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2023/08/09
This Science Research Conference is the first of its kind solely focused on detailing current advances, critical challenges, and future directions of basic, translational, and clinical cholangiocarcinoma (CCA) research.
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2023/08/01
The Hematologic Malignancies Conference is focused on all aspects of the biology of hematological malignancies including molecular pathogenesis of blood cancers, control of stem cell function and differentiation, chromatin biology, and new therapeutic strategies.
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2023/07/27
Bevacizumab is a medication that could treat lots of types of cancers and a specific eye disease. It is usually sold under the brand name Avastin. Alpha Lifetech could supply you with high purity and low endotoxin level Bevacizumab biosimilar. The Bevacizumab biosimilar provided by Alpha Lifetech is only for research use.
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2023/06/28
Western blotting, also known as protein immunoblotting, is an analytical technique widely used in molecular biology, biochemistry and immunogenetics. It is employed to detect specific proteins in a tissue homogenate or extract sample. This method has become an essential tool for researchers and scientists in various fields, enabling them to study protein expression, modification and interaction.
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2023/06/19
Cell line characterization is a critical step in developing and manufacturing biopharmaceuticals, as well as in basic research and drug discovery. Ensuring the quality, safety, and efficacy of cell lines is essential for producing reliable and reproducible results. Alpha Lifetech Inc., a provider of life science products and services, offers a comprehensive cell line characterization service to meet the needs of researchers and biopharmaceutical companies.
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2023/06/14
For decades, Immortalized cell lines have been a cornerstone of scientific research, making breakthroughs and advancements in the fields of medicine, genetics and biotechnology. These cell lines, genetically modified to increase indefinitely, have become invaluable tools for researchers worldwide.
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2023/06/12
Antibodies have become indispensable tools in biomedical research, diagnostics and therapeutics. Camelid polyclonal antibodies derived from camelids such as llamas and alpacas have unique advantages over conventional antibodies due to their distinct structural properties and high stability.
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2023/06/08
Alpha Lifetech Inc. provides a complete and customizable bovine polyclonal antibody service to meet the specific needs of researchers in various fields. With a focus on quality, reliability, and customer satisfaction, Alpha Lifetech Inc. ensures the production of high-performance antibodies for a wide range of applications.
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2023/06/06
The rabbit polyclonal antibody is a collection of antibodies produced by different B cells in a rabbit, which recognize multiple epitopes (or sites) on the same antigen. Rabbits are commonly used as laboratory animals for producing polyclonal antibodies because of their ability to create a large volume of antibodies.
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2023/05/22
In the realm of biotechnology and scientific research, obtaining high-quality antibodies is essential for accurate and reliable results. Alpha Lifetech Inc. has developed a groundbreaking monoclonal antibody technology specifically tailored for rabbit monoclonal antibody production.
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2023/05/30
Alpha Lifetech Inc. is a biotechnology company that develops and produces high-quality nanoparticles and other advanced materials for various applications.
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2023/05/26
Alpha Lifetech Inc., with its expertise in naïve phage display library panning construction technology, is dedicated to providing high-quality results to support your research needs. Our advanced approach to library construction and panning ensures that researchers can rely on their services for cutting-edge solutions in various scientific applications.
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2023/05/16
Phage display technology is a molecular biology technique that uses bacteriophages to connect proteins with the genetic information that encodes them, allowing the study of protein-protein, protein-peptide, and protein-DNA interactions.
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2023/05/11
Alpaca VHH antibodies are also known as single-domain antibodies or nanobodies. They are unique fragments of antibodies derived from heavy-chain-only antibodies in camelids such as alpacas and lamas. These small, stable, and highly soluble antibodies possess remarkable specificity and affinity, making them ideal candidates for use in various research applications, diagnostics, and therapeutics.
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2023/04/19
Human respiratory syncytial virus (HRSV) is a member of the Pneumoviridae genus and contains a single-stranded non-segmented negative-sense RNA genome approximately 15,200 nt in length. Its genome contains 10 open reading frames (ORFs) which encode 11 proteins.
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2023/04/27
Biosimilar antibodies can be used to study the biological effects of a drug without the need for expensive pharmaceutical-grade therapeutic products. They can be used in a variety of research applications, including functional tests, flow cytometry, ELISA, immunohistochemistry, pharmacokinetic tests, and others.
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2023/04/25
The majority of antibodies in use today were selected on the basis of their affinity for binding. Today, however, therapeutic drugs are increasingly looking for antibodies that not only bind, but also can alter the function cell surface signaling component.
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2023/03/28
Monoclonal antibodies (mAbs) are immunoglobulins designed to target a specific epitope on an antigen. The antigen-binding region of the mAb is formed by the variable domains of the heavy and light chains and contains the complementarity-determining region that imparts the high specificity for the target antigen.
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2023/03/21
Antibodies are large Y-shaped proteins called immune globulins that are produced by B cells. Due to the strong affinity of an antibody to one particular molecule, they are widely used in research to identify and detect target proteins of interest.
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2023/03/13
Cell lines are in vitro model systems that are used extensively in various areas of biological research. Their utility is mainly related to their ability to supply an undefined source of biological material for experimental purposes. Under the right conditions and through appropriate controls, certified cancer cell lines retain most of the genetic properties of the original cancer.
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2023/03/07
Human primary cells are cells isolated directly from human tissues. The majority of human primary cells are terminally differentiated cells with a highly specific type and high level of function. They closely mimic the physiological state of cells in vivo and are expected to maintain their in vivo functions under optimal conditions for a short period of time. Human primary cells are established as an important tool for in vitro cell-based assays or for generating in vivo models.
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2023/02/22
Primary cells refer to cells that are isolated or harvested directly from living tissue or organs. Primary cells closely mimic the physiological state of cells in vivo and are expected to maintain their in vivo functions under optimal conditions for a short period of time.
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2023/02/27
The animal cell model is an alternative for the in vivo study of cell biology. As models for human systems, researchers can use animal cells to assess new treatments prior to applying the results of this research to humans. Animal primary cell cultivation can be used in a variety of fields, from basic research to advanced research.
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2023/02/13
Primary cells are derived from tissue and not modified, so they are more similar to the in vivo state and exhibit normal physiology. Therefore, they provide excellent systems models to study the normal physiology and biochemistry of cells, and the effects of drugs and toxic compounds on cells.
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2023/02/01
Cancer is considered to be a family of diseases that share a common set of characteristics such as reprogrammed energy metabolism, uncontrolled cell growth, tumor angiogenesis, and avoidance of immune destruction, referred to as cancer hallmarks. Cancer is one of the highest researched diseases and cancer prevention is becoming understood and accepted as a shared responsibility.
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2023/01/12
Enzyme-linked immunosorbent assay (ELISA) is one of the most specific and straightforward assays for detecting biomolecules. It is an exceptionally powerful and versatile technique.
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2023/01/17
Enzyme-linked immunosorbent assay (ELISA) is one of the most specific and straightforward assays for detecting biomolecules. ELISA is a useful tool for measuring changes in biological processes in vivo or in vitro and its test samples can include plasma, serum, saliva, urine, tissue culture media, cells lysates and other materials.
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2023/01/28
The ready-to-use ELISA kits have been optimized and validated to maximize the signal quality for specificity, sensitivity, coefficient of variation and other parameters. However, when a kit is unavailable for the specific target or is not optimized for the specific parameter required, labs may need to develop their own test. While ELISA is a powerful assay, it can be challenging to develop and optimize a specific test.
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2023/01/04
Alpha Lifetech Inc. has been engaged in protein expression services for many years, and our scientists have rich experience. With our proprietary Codon Optimization Technology, Alpha Lifetech Inc. has extremely promoted the expression level of target recombinant proteins in most systems including E. coli, yeast and mammalian host.
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2022/12/17
Custom Services Christmas Promotion: Greetings from Alpha Lifetech Inc! Our team at Alpha Lifetech wishes you a very merry Christmas and a happy New Year!
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2022/12/13
A cell line is a permanently established cell culture that will proliferate indefinitely given appropriate fresh medium and space. Lines differ from cell strains in that they become immortalized.
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2022/12/01
This inaugural Science Research Conference (SRC) provides a platform for probe developers and probe users to share knowledge, expertise, and challenges that can guide the development of probes towards new and more critical biochemical targets and accelerate their adoption by biomedical and clinical researchers.
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2022/11/15
The conference's main themes are: 1) Structure and regulation of protein phosphatases; 2) Roles of protein phosphatases in cancer and other human diseases; 3) Druggability of phosphatases and validating them as therapeutic targets.
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2022/10/21
It is the largest conference solely dedicated to cancer immunotherapy on Nov 8-Nov 12, 2022, in Boston Convention and Exhibition Center, 415 Summer Street Boston.
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2022/10/09
Discovery on Target will be held on Octoer 17-20, 2022 in Boston. Discovery on Target (DOT) highlights advances in current and emerging "hot" targets and technologies, as well as target validation strategies for the discovery and development of novel therapeutic agents ranging from biologics to small molecules.
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2022/09/29
BioProcess International will be held in Boston Convention and Exhibition Center on Sep.27-30, 2022. Each year, BPI's scientific agenda includes 200+ of the industry's top scientists to present the latest updates on how to improve efficiencies across all phases of biopharmaceutical development and production.
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2022/08/23
Biological products are the fastest-growing class of therapeutic products in the United States. When patients are prescribed a biological product, biosimilar and interchangeable products can offer additional treatment options, potentially lowering health care costs.
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2018/12/03
Alpha Lifetech Inc. is a premier supplier of bio reagents and provides drug discovery services to worldwide scientists. The company was founded by a group of scientists with extensive experience in protein expression, antibody development, library construction, stable cell line construction, cell culture, gene editing, and other related services.
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2022/06/06
Advances in single-cell technologies have not only made it possible to analyze multiple molecular families in individual cells, they have also enabled scientists to parse through limitations in data analysis arising from the intercellular diversity of measured parameters. Although single-cell sequencing is now widely available, techniques to detect epigenetic markers and transcription at single-cell resolution in a combined protocol has been unavailable until now
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2022/06/27
CAR-T cell therapy has had success in treating children and adults with leukemia and lymphoma. However, CAR T cells have not had the same success against solid tumors, with problems involving persistence and function
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2018/06/08
A study published Friday in the journal Cell Stem Cell reported results from the first-in-human phase 1 clinical trial of an experimental monoclonal antibody-based drug. The potential new drug is proved to have measurably inhibited chronic leukemia cancer (CLL) cells' ability to self-renew and resisted their terminal differentiation and senescence.
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2020/08/14
Cellular senescence is characterized by stable cell-cycle arrest and a secretory program that modulates the tissue microenvironment. Physiologically, senescence serves as a tumour-suppressive mechanism that prevents the expansion of premalignant cells and has a beneficial role in wound-healing responses. Pathologically, the aberrant accumulation of senescent cells generates an inflammatory milieu that leads to chronic tissue damage and contributes to diseases such as liver and lung fibrosis
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2020/08/06
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led to the death of more than 160,000 individuals and caused worldwide social and economic disruption.
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2019/05/22
71st AACC Annual Scientific Meeting & Clinical Lab Expo will be held in August 4-8, 2019 at Anaheim Convention Center, Anaheim, CA USA.
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2018/08/06
An international team of scientists reports that therapeutic antibodies may be the best way to stop the Ebola virus. Their study (“Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection”), published in Cell, suggests new therapies should disable the Ebola virus's infection machinery and spark the patient's immune system to fight the virus.