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Custom Bovine Polyclonal Antibody Service

Alpha Lifetech Inc. provides a complete and customizable bovine polyclonal antibody service to meet the specific needs of researchers in various fields. With a focus on quality, reliability, and customer satisfaction, Alpha Lifetech Inc. ensures the production of high-performance antibodies for a wide range of applications.

 

Custom Bovine (Cow/Cattle) Polyclonal Antibody Production Service

 

Some of the bovine (cow/cattle) antibodies have a unique character in that around 10% of them have an ultra-long CDR3 loop (red part) which extends out of the Fab domain in the form of a "stalk." Then, this long CDR3 antibody stalk forms a "knob", showing most of the binding activity of the antibody. This long CDR3 stalk is stabilized by both antiparallel beta-sheets leading to and from the knob region and by forces from residues in the other CDR loops. The knob region often contains 4 to 12 cysteine residues, which contributes to the formation of disulfide bonds, thus helping to maintain its stability. These characteristics of bovine antibodies give rise to an extended binding domain, which can reach into clefts, canyons and pores in proteins unreachable by typical IgG antibodies.

 

The custom bovine polyclonal antibody service includes designing and producing antibodies tailored to the specific requirements of researchers. This service encompasses antigen design, immunization, antibody production, purification, validation, and quality control. The custom approach ensures that researchers receive antibodies with high affinity and specificity for their target antigens.

 

Advantages of Bovine Polyclonal Antibodies

 

High affinity and specificity: Bovine polyclonal antibodies are known for their high affinity and specificity, making them ideal for various applications, including ELISA, Western Blot, and immunohistochemistry.

Broad applicability: Because of their heterogeneity, polyclonal antibodies can recognize multiple epitopes on the target antigen, making them suitable for various species and experimental conditions.

Cost-effective and scalable production: The production of bovine polyclonal antibodies is more cost-effective than that of monoclonal antibodies, and it can be easily scaled up to meet the growing demand.

However, there are also challenges associated with bovine polyclonal antibodies, such as batch-to-batch variability and the potential for cross-reactivity. To address these issues, custom bovine polyclonal antibody services employ rigorous quality control measures and stringent validation processes to ensure the reliability and consistency of the antibodies produced.

 

Service Features

 

--Custom antigen design and synthesis

--Bovine immunization and antibody production

--Purification and validation of antibodies

--Quality control and guaranteed performance

--Competitive pricing and flexible service options

 

Alpha Lifetech Inc. provides a comprehensive custom bovine polyclonal antibody service, tailored to meet your research needs. Our experienced team will work closely with you to design and produce high-quality and reliable antibodies for your specific target antigens. For more information or to request a quote, don't hesitate to get in touch with us to discuss your project requirements. Our expert team is ready to assist you in achieving your research goals.