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Gold conjugation kits are a type of bioconjugation kit that simplifies the process of gold conjugation for researchers in the field of biomedical research. These kits provide all the necessary reagents and protocols required for the conjugation of gold nanoparticles with specific molecules, such as antibodies or peptides. The principle is that the covalent coupling between antibody/protein and gold nanoparticles can be realized simply and quickly through primary amine groups (such as lysine) on antibody/protein. The operation time of gold nanoparticles conjugation process is about 3 minutes, and the conjugation can be used within 30 minutes.

 

Fig.1 Gold Conjugation Kits

 

Benefits of Gold Conjugation Kits

 

--Streamlined Process: Gold conjugation kits provide a streamlined process for the conjugation of gold nanoparticles with specific molecules, such as antibodies or peptides. They eliminate the waste of time and money caused by researchers purchasing single reagents and developing their own schemes.

--Consistent Results: Gold conjugation kits provide consistent results, ensuring that the conjugation process is reproducible and reliable. This is important for researchers who need to produce large quantities of gold conjugates for their experiments.

--Cost-Effective: Gold conjugation kits can be cost-effective compared to sourcing individual reagents and developing protocols. They also eliminate the need for specialized equipment, which can be expensive.

 

Applications in Biomedical Research

 

--Cancer Diagnosis and Therapy: Gold conjugation kits have been used for the conjugation of gold nanoparticles with specific antibodies for targeted delivery and imaging of cancer cells. They can also be used for the detection of cancer biomarkers in blood and urine samples.

--Infectious Disease Diagnosis: Gold conjugation kits have been used for the conjugation of gold nanoparticles with specific antibodies or nucleic acids for the detection of infectious agents, such as viruses and bacteria, in blood and urine samples.

--Imaging: Gold conjugation kits have been used for the conjugation of gold nanoparticles with specific molecules, such as peptides or antibodies, for imaging purposes, such as computed tomography (CT) and magnetic resonance imaging (MRI). They can enhance the contrast of the images and improve the accuracy of the diagnosis.

 

Product Description

 

Alpha Lifetech Inc. gold conjugation kits allow antibodies or proteins to be covalently attached to ultra-stable gold nanoparticles at very high OD. The operation is quick and simple, the researcher simply pipettes the biomolecule into a vial containing the nanoparticles of the gold conjugation kits.

The gold conjugation kits provided by Alpha Lifetech Inc. have consistent and reproducible results which are important for researchers who need to produce large quantities of gold conjugates for their experiments.

The nanoparticles in this kit are supplied as a freeze-dried mixture. The resulting covalent conjugates are more stable than those prepared by passive adsorption methods,and all antibodies can be labelled at a single pH.

Quality advantage

1. Conjugation is quick and simple, taking about two minutes. 

2. High repeatability and high activity.

3. Various specifications of kits are available.

4. Fully scalable - Simple transition from R&D to production.

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