Among the different types of magnetic particles, lanthanide-based magnetic particles have emerged as a promising class of materials due to their unique magnetic and optical properties. Lanthanide-based magnetic particles are a type of magnetic nanoparticle that contains lanthanide ions, such as europium, gadolinium, and terbium, as the magnetic component. These particles can be synthesized by various methods, including co-precipitation, solvothermal synthesis, hydrothermal synthesis, and microwave-assisted synthesis. The magnetic core material can be iron oxide, cobalt or nickel, and the lanthanide ions are usually doped into the core material or coated onto the surface of the particle.

Lanthanide-based magnetic particles have unique magnetic and optical properties that make them attractive for various applications. The magnetic properties of these particles are determined by the lanthanide ions, which have a high magnetic moment and paramagnetic properties. The optical properties of these particles are due to the lanthanide ions' ability to emit light in response to excitation by an external energy source, such as UV light. This property is known as the lanthanide minescence, and it has been used in biosensing and imaging applications.

Biomedical Applications of Lanthanide-based Magnetic Particles

Magnetic particles have been widely used in biomedical applications due to their unique properties, such as high magnetic moment, biocompatibility, and surface functionalization: including magnetic resonance imaging (MRI), drug delivery, and biosensing.

--MRI: These particles can enhance the contrast of images due to their high magnetic moment and paramagnetic properties.

--Drug Delivery: These particles can be functionalized with drugs or targeting ligands and used for targeted drug delivery.      

--Biosensing: These particles can be used as labels for the detection of biomolecules due to their unique optical properties.

Lanthanide-based magnetic particles have several advantages over other types of magnetic particles in biomedical applications. First, they have a high magnetic moment and paramagnetic properties, which make them attractive for MRI and magnetic hyperthermia. Second, they have unique optical properties, such as lanthanide luminescence, which can be used for biosensing and imaging applications. Third, they can be functionalized with drugs or targeting ligands and used for targeted drug delivery. Fourth, they are biocompatible and can be used in vivo without causing significant toxicity or immune response.

Fig. 1 sensors

Production of Lanthanide-based Magnetic Particles

The production of Lanthanide-based magnetic particles requires careful consideration of the synthesis method, the choice of core material, and the doping or coating of lanthanide ions.

--Production methods: co-precipitation, solvothermal synthesis, hydrothermal synthesis and microwave-assisted synthesis. Co-precipitation involves the precipitation of the magnetic core material in the presence of the lanthanide ions. Solvothermal synthesis and hydrothermal synthesis use high pressure and temperature to produce the particles, while microwave-assisted synthesis uses microwave radiation to heat the reaction mixture.

--Core materials: Iron oxide is the most commonly used core material due to its magnetic properties and biocompatibility. Cobalt and nickel are also used as core materials. The size and shape of the core material also affect the magnetic properties of the particles.

--Doping of lanthanide ions: Lanthanide ions, such as europium, gadolinium, and terbium, are doped or coated onto the surface of the magnetic particles to impart their unique optical properties.

Product Description

Magnetic nanoparticles have a series of unique and superior physical and chemical properties, such as magnetic orientation, biocompatibility, small size effect, surface effect, etc., which can simplify the complicated traditional experimental methods and shorten the experimental time. It is a new and efficient reagent. Alpha Lifetech Inc. provides a range of active magnetic particles in a variety of surface materials for research and commercial applications.  

We provide lanthanide-base magnetic particles, lanthanide-based magnetic particles are superparamagnetic magnetic particles formed by the reaction of a strong lanthanide (Ln) single-electron oxidant with magnetite under high-power ultrasound irradiation. These particles do not accumulate easily in water suspensions/ferrofluids. Moreover, lanthanides easily react with Lewis base to achieve further functionalization. Lanthanides exhibit strong electromagnetic and optical properties, and most of them have a strong magnetic field.

Quality advantage

1.It is not easy to aggregate in aqueous suspensions due to electrostatic repulsion.

2.High superparamagnetic

3.Easy conjugation and separation

4.High surface area

Applications

1.Magnetic resonance imaging (MRI)

2.Biological imaging

3.Nanometer temperature measurement

4.Cancer diagnosis

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Lanthanide-Based Magnetic Particles Product List