Product Datasheet
|
Catalog Number |
ALP64514 |
|
Product Name |
Recombinant Human 5T4 Protein, Avi Tag, His Tag |
|
Description |
ALP64514 Recombinant Human 5T4 Protein, Avi Tag, His Tag is produced in HEK293 Cells and the target gene encoding Ser32-Ser355 is expressed with a AVI, 6His tag at the C-terminus. |
|
Official Symbol |
5T4 |
|
Expression Host |
HEK293 Cells |
|
Alias |
Human M6P1 Protein, 5T4 |
|
Species |
Human |
|
Size |
50ug, 100ug |
|
Purification |
Affinity Purification |
|
Endotoxin |
<1.0 EU/ug determined by the LAL method |
|
Purity |
>90%-95% as determined by SDS-PAGE |
|
Buffer |
Supplied in PBS, pH7.4 |
|
Uniprot |
|
|
Background |
Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap(LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
|
Storage |
For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles. |
|
Shipping Condition |
Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice. |
|
Note |
This product is for research use only. This product can not be used for human. |
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