Product Datasheet
|
Catalog Number |
ALP64519 |
|
Product Name |
Recombinant Human CD3E Protein, mFc Tag |
|
Description |
ALP64519 Recombinant Human CD3E Protein, mFc Tag is produced in HEK293 Cells and the target gene encoding Gln22-Thr48 is expressed with a mFc tag at the C-terminus. |
|
Official Symbol |
CD3E |
|
Expression Host |
HEK293 Cells |
|
Alias |
T-Cell Surface Glycoprotein CD3 Epsilon Chain, CD3E |
|
Species |
Human |
|
Size |
50ug, 100ug |
|
Purification |
Affinity Purification |
|
Endotoxin |
<1.0 EU/ug determined by the LAL method |
|
Purity |
>90%-95% as determined by SDS-PAGE |
|
Buffer |
Supplied in PBS, pH7.4 |
|
Uniprot |
|
|
Background |
T-Cell Surface Glycoprotein CD3 ε Chain(CD3ε) is a single-pass type I membrane protein. CD3ε contains 1 Ig-like(immunoglobulin-like) domain and 1 ITAM domain. CD3ε is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex(TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs(ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. |
|
Storage |
For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles. |
|
Shipping Condition |
Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice. |
|
Note |
This product is for research use only. This product can not be used for human. |
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