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Product Datasheet

Catalog Number

ALP64523

Product Name

Recombinant Human Biotinylated FGL1 Protein, Avi Tag, His Tag

Description

ALP64523 Recombinant Human Biotinylated FGL1 Protein, Avi Tag, His Tag is produced in HEK293 Cells and the target gene encoding Leu23-Ile312 is expressed with a AVI, 6His tag at the C-terminus.

Official Symbol

FGL1

Protein Family

Fibronogen Superfamily

Expression Host

HEK293 Cells

Alias

Fibrinogen-like protein 1, FGL1

Species

Human

Size

50ug, 100ug

Purification

Affinity Purification

Endotoxin

<1.0 EU/ug determined by the LAL method

Purity

>90% as determined by SDS-PAGE

Buffer

Supplied in 20mM Tris, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH8

Uniprot

Q08830

Background

Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

 

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