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Product Datasheet

Catalog Number

ALP64524

Product Name

Recombinant Human TNFRSF17 Protein, Fc Tag, Avi Tag

Description

ALP64524 Recombinant Human TNFRSF17 Protein, Fc Tag, Avi Tag is produced in HEK293 Cells and the target gene encoding Met1-Ala54 is expressed with a Fc, Avi tag at the C-terminus.

Official Symbol

TNFRSF17

Protein Family

TNF Receptor Superfamily

Expression Host

HEK293 Cells

Alias

CD269, Bcma

Species

Human

Size

50ug, 100ug

Purification

Affinity Purification

Endotoxin

<1.0 EU/ug determined by the LAL method

Purity

>90% as determined by SDS-PAGE

Buffer

Supplied in PBS, pH7.4

Uniprot

Q6PE46

Background

B cell maturation protein(BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily(TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid(aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

 

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